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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
16.06
Human Site:
S289
Identified Species:
29.44
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
S289
L
G
K
T
K
D
L
S
Q
N
S
N
E
M
S
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
S364
L
G
K
T
K
D
L
S
Q
N
S
N
E
M
S
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
H246
S
G
M
F
V
N
I
H
P
S
G
V
K
T
E
Dog
Lupus familis
XP_854792
605
67422
S290
L
G
K
T
K
A
L
S
Q
N
S
N
E
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
G281
K
D
L
S
H
C
G
G
D
M
P
V
V
Q
S
Rat
Rattus norvegicus
Q8VIJ4
590
65509
G281
K
D
L
S
H
C
G
G
D
L
P
V
V
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
S253
Q
S
S
S
T
D
L
S
M
I
E
S
L
S
N
Chicken
Gallus gallus
O42101
501
57084
T193
N
H
T
A
L
P
P
T
D
Y
D
R
S
P
F
Frog
Xenopus laevis
Q66J63
637
70793
S323
S
L
A
N
L
N
K
S
K
D
L
P
Q
T
N
Zebra Danio
Brachydanio rerio
Q06725
411
45463
S103
C
K
S
F
F
K
R
S
V
R
R
N
L
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
S235
V
R
R
N
L
T
Y
S
C
R
G
S
R
N
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
L282
K
P
G
S
P
V
M
L
Q
N
T
Q
D
Y
M
Sea Urchin
Strong. purpuratus
Q26622
583
63834
Y274
P
S
H
S
Q
Q
I
Y
S
P
S
Q
T
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
6.6
93.3
N.A.
6.6
6.6
N.A.
20
0
6.6
13.3
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
13.3
13.3
N.A.
40
6.6
40
13.3
N.A.
26.6
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
16
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
16
0
0
0
24
0
0
24
8
8
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
24
0
8
% E
% Phe:
0
0
0
16
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
31
8
0
0
0
16
16
0
0
16
0
0
0
0
% G
% His:
0
8
8
0
16
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% I
% Lys:
24
8
24
0
24
8
8
0
8
0
0
0
8
0
0
% K
% Leu:
24
8
16
0
24
0
31
8
0
8
8
0
16
8
0
% L
% Met:
0
0
8
0
0
0
8
0
8
8
0
0
0
24
8
% M
% Asn:
8
0
0
16
0
16
0
0
0
31
0
31
0
8
16
% N
% Pro:
8
8
0
0
8
8
8
0
8
8
16
8
0
8
0
% P
% Gln:
8
0
0
0
8
8
0
0
31
0
0
16
8
16
8
% Q
% Arg:
0
8
8
0
0
0
8
0
0
16
8
8
8
0
0
% R
% Ser:
16
16
16
39
0
0
0
54
8
8
31
16
8
8
39
% S
% Thr:
0
0
8
24
8
8
0
8
0
0
8
0
8
24
0
% T
% Val:
8
0
0
0
8
8
0
0
8
0
0
24
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
8
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _